AMP kinase promotes glioblastoma bioenergetics and tumour growth
AMP kinase promotes glioblastoma bioenergetics and tumour growth
About this item
Full title
Author / Creator
Chhipa, Rishi Raj , Fan, Qiang , Anderson, Jane , Muraleedharan, Ranjithmenon , Huang, Yan , Ciraolo, Georgianne , Chen, Xiaoting , Waclaw, Ronald , Chow, Lionel M. , Khuchua, Zaza , Kofron, Matthew , Weirauch, Matthew T. , Kendler, Ady , McPherson, Christopher , Ratner, Nancy , Nakano, Ichiro , Dasgupta, Nupur , Komurov, Kakajan and Dasgupta, Biplab
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Stress is integral to tumour evolution, and cancer cell survival depends on stress management. We found that cancer-associated stress chronically activates the bioenergetic sensor AMP kinase (AMPK) and, to survive, tumour cells hijack an AMPK-regulated stress response pathway conserved in normal cells. Analysis of The Cancer Genome Atlas data revea...
Alternative Titles
Full title
AMP kinase promotes glioblastoma bioenergetics and tumour growth
Authors, Artists and Contributors
Author / Creator
Fan, Qiang
Anderson, Jane
Muraleedharan, Ranjithmenon
Huang, Yan
Ciraolo, Georgianne
Chen, Xiaoting
Waclaw, Ronald
Chow, Lionel M.
Khuchua, Zaza
Kofron, Matthew
Weirauch, Matthew T.
Kendler, Ady
McPherson, Christopher
Ratner, Nancy
Nakano, Ichiro
Dasgupta, Nupur
Komurov, Kakajan
Dasgupta, Biplab
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6113057
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6113057
Other Identifiers
ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/s41556-018-0126-z
