Sodium Thiosulfate for Protection from Cisplatin-Induced Hearing Loss
Sodium Thiosulfate for Protection from Cisplatin-Induced Hearing Loss
About this item
Full title
Author / Creator
Brock, Penelope R , Maibach, Rudolf , Childs, Margaret , Rajput, Kaukab , Roebuck, Derek , Sullivan, Michael J , Laithier, Véronique , Ronghe, Milind , Dall’Igna, Patrizia , Hiyama, Eiso , Brichard, Bénédicte , Skeen, Jane , Mateos, M. Elena , Capra, Michael , Rangaswami, Arun A , Ansari, Marc , Rechnitzer, Catherine , Veal, Gareth J , Covezzoli, Anna , Brugières, Laurence , Perilongo, Giorgio , Czauderna, Piotr , Morland, Bruce and Neuwelt, Edward A
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
Cisplatin is an effective treatment for hepatoblastoma but often leads to lifelong irreversible hearing loss. The addition of sodium thiosulfate 6 hours after cisplatin administration preserved the antitumor effect and led to a lower risk of hearing loss (33% vs. 63%).
Alternative Titles
Full title
Sodium Thiosulfate for Protection from Cisplatin-Induced Hearing Loss
Authors, Artists and Contributors
Author / Creator
Maibach, Rudolf
Childs, Margaret
Rajput, Kaukab
Roebuck, Derek
Sullivan, Michael J
Laithier, Véronique
Ronghe, Milind
Dall’Igna, Patrizia
Hiyama, Eiso
Brichard, Bénédicte
Skeen, Jane
Mateos, M. Elena
Capra, Michael
Rangaswami, Arun A
Ansari, Marc
Rechnitzer, Catherine
Veal, Gareth J
Covezzoli, Anna
Brugières, Laurence
Perilongo, Giorgio
Czauderna, Piotr
Morland, Bruce
Neuwelt, Edward A
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6117111
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6117111
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1801109