ATR kinase inhibitor AZD6738 potentiates CD8+ T cell–dependent antitumor activity following radiatio...
ATR kinase inhibitor AZD6738 potentiates CD8+ T cell–dependent antitumor activity following radiation
About this item
Full title
Author / Creator
Vendetti, Frank P. , Karukonda, Pooja , Clump, David A. , Teo, Troy , Lalonde, Ronald , Nugent, Katriana , Ballew, Matthew , Kiesel, Brian F. , Beumer, Jan H. , Sarkar, Saumendra N. , Conrads, Thomas P. , O’Connor, Mark J. , Ferris, Robert L. , Tran, Phuoc T. , Delgoffe, Greg M. and Bakkenist, Christopher J.
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
More information
Scope and Contents
Contents
DNA-damaging chemotherapy and radiation therapy are integrated into the treatment paradigm of the majority of cancer patients. Recently, immunotherapy that targets the immunosuppressive interaction between programmed death 1 (PD-1) and its ligand PD-L1 has been approved for malignancies including non-small cell lung cancer, melanoma, and head and n...
Alternative Titles
Full title
ATR kinase inhibitor AZD6738 potentiates CD8+ T cell–dependent antitumor activity following radiation
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6118586
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6118586
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI96519
