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Mitochondrial metabolism in pulmonary hypertension: beyond mountains there are mountains

Mitochondrial metabolism in pulmonary hypertension: beyond mountains there are mountains

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6118596

Mitochondrial metabolism in pulmonary hypertension: beyond mountains there are mountains

About this item

Full title

Mitochondrial metabolism in pulmonary hypertension: beyond mountains there are mountains

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2018-09, Vol.128 (9), p.3704-3715

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Pulmonary hypertension (PH) is a heterogeneous and fatal disease of the lung vasculature, where metabolic and mitochondrial dysfunction may drive pathogenesis. Similar to the Warburg effect in cancer, a shift from mitochondrial oxidation to glycolysis occurs in diseased pulmonary vessels and the right ventricle. However, appreciation of metabolic e...

Alternative Titles

Full title

Mitochondrial metabolism in pulmonary hypertension: beyond mountains there are mountains

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6118596

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6118596

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI120847

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