VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma
VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma
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Full title
Author / Creator
Zhang, Jing , Wu, Tao , Simon, Jeremy , Takada, Mamoru , Saito, Ryoichi , Fan, Cheng , Liu, Xian-De , Jonasch, Eric , Xie, Ling , Chen, Xian , Yao, Xiaosai , Teh, Bin Tean , Tan, Patrick , Zheng, Xingnan , Li, Mingjie , Lawrence, Cortney , Fan, Jie , Geng, Jiang , Liu, Xijuan , Hu, Lianxin , Wang, Jun , Liao, Chengheng , Hong, Kai , Zurlo, Giada , Parker, Joel S , Auman, J Todd , Perou, Charles M , Rathmell, W Kimryn , Kim, William Y , Kirschner, Marc W , Kaelin, Jr, William G , Baldwin, Albert S and Zhang, Qing
Publisher
United States: The American Association for the Advancement of Science
Journal title
Language
English
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Publication information
Publisher
United States: The American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Inactivation of the von Hippel-Lindau (VHL) E3 ubiquitin ligase protein is a hallmark of clear cell renal cell carcinoma (ccRCC). Identifying how pathways affected by VHL loss contribute to ccRCC remains challenging. We used a genome-wide in vitro expression strategy to identify proteins that bind VHL when hydroxylated. Zinc fingers and homeoboxes...
Alternative Titles
Full title
VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma
Authors, Artists and Contributors
Author / Creator
Wu, Tao
Simon, Jeremy
Takada, Mamoru
Saito, Ryoichi
Fan, Cheng
Liu, Xian-De
Jonasch, Eric
Xie, Ling
Chen, Xian
Yao, Xiaosai
Teh, Bin Tean
Tan, Patrick
Zheng, Xingnan
Li, Mingjie
Lawrence, Cortney
Fan, Jie
Geng, Jiang
Liu, Xijuan
Hu, Lianxin
Wang, Jun
Liao, Chengheng
Hong, Kai
Zurlo, Giada
Parker, Joel S
Auman, J Todd
Perou, Charles M
Rathmell, W Kimryn
Kim, William Y
Kirschner, Marc W
Kaelin, Jr, William G
Baldwin, Albert S
Zhang, Qing
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6154478
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6154478
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aap8411
