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Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis

Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6187131

Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis

About this item

Full title

Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2018-10, Vol.115 (41), p.10381-10386

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Nuclear hormone receptors (NRs), such as retinoic acid receptors (RARs), play critical roles in vertebrate development and homeostasis by regulating target gene transcription. Their activity is controlled by ligand-dependent release of corepressors and subsequent recruitment of coactivators, but how these individual receptor modes contribute to dev...

Alternative Titles

Full title

Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6187131

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6187131

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1809480115

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