A functional genomics screen reveals a strong synergistic effect between docetaxel and the mitotic g...
A functional genomics screen reveals a strong synergistic effect between docetaxel and the mitotic gene DLGAP5 that is mediated by the androgen receptor
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Based on a molecular classification of prostate cancer using gene expression pathway signatures, we derived a set of 48 genes in critical pathways that significantly predicts clinical outcome in all tested patient cohorts. We tested these genes in a functional genomics screen in a panel of three prostate cancer cell lines (LNCaP, PC3, DU145), using...
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A functional genomics screen reveals a strong synergistic effect between docetaxel and the mitotic gene DLGAP5 that is mediated by the androgen receptor
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6195526
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6195526
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2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-018-1115-7
