Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognitio...
Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Severe acute respiratory syndrome coronavirus (SARS-CoV) emerged in 2002 as a highly transmissible pathogenic human betacoronavirus. The viral spike glycoprotein (S) utilizes angiotensin-converting enzyme 2 (ACE2) as a host protein receptor and mediates fusion of the viral and host membranes, making S essential to viral entry into host cells and ho...
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Full title
Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6200764
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6200764
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-34171-7
