Tau filaments from multiple cases of sporadic and inherited Alzheimer’s disease adopt a common fold
Tau filaments from multiple cases of sporadic and inherited Alzheimer’s disease adopt a common fold
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Language
English
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Contents
The ordered assembly of tau protein into abnormal filaments is a defining characteristic of Alzheimer’s disease (AD) and other neurodegenerative disorders. It is not known if the structures of tau filaments vary within, or between, the brains of individuals with AD. We used a combination of electron cryo-microscopy (cryo-EM) and immuno-gold negativ...
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Full title
Tau filaments from multiple cases of sporadic and inherited Alzheimer’s disease adopt a common fold
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6208733
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6208733
Other Identifiers
ISSN
0001-6322
E-ISSN
1432-0533
DOI
10.1007/s00401-018-1914-z
