Activated β-catenin in Foxp3+ regulatory T cells links inflammatory environments to autoimmunity
Activated β-catenin in Foxp3+ regulatory T cells links inflammatory environments to autoimmunity
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Foxp3
+
regulatory T cells (T
reg
cells) are the central component of peripheral immune tolerance. Whereas a dysregulated T
reg
cytokine signature has been observed in autoimmune diseases, the regulatory mechanisms underlying pro- and anti-inflammatory cytokine production are elusive. Here, we identify an imbalance between the cyt...
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Full title
Activated β-catenin in Foxp3+ regulatory T cells links inflammatory environments to autoimmunity
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6240373
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6240373
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-018-0236-6