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Activated β-catenin in Foxp3+ regulatory T cells links inflammatory environments to autoimmunity

Activated β-catenin in Foxp3+ regulatory T cells links inflammatory environments to autoimmunity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6240373

Activated β-catenin in Foxp3+ regulatory T cells links inflammatory environments to autoimmunity

About this item

Full title

Activated β-catenin in Foxp3+ regulatory T cells links inflammatory environments to autoimmunity

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2018-12, Vol.19 (12), p.1391-1402

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Foxp3
+
regulatory T cells (T
reg
cells) are the central component of peripheral immune tolerance. Whereas a dysregulated T
reg
cytokine signature has been observed in autoimmune diseases, the regulatory mechanisms underlying pro- and anti-inflammatory cytokine production are elusive. Here, we identify an imbalance between the cyt...

Alternative Titles

Full title

Activated β-catenin in Foxp3+ regulatory T cells links inflammatory environments to autoimmunity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6240373

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6240373

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/s41590-018-0236-6

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