Fatty acids promote fatty liver disease via the dysregulation of 3-mercaptopyruvate sulfurtransferas...
Fatty acids promote fatty liver disease via the dysregulation of 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway
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Author / Creator
Li, Meng , Xu, Chengfu , Shi, Junping , Ding, Jiexia , Wan, Xingyong , Chen, Dahua , Gao, Jianguo , Li, Chunxiao , Zhang, Jie , Lin, Yiming , Tu, Zhenhua , Kong, Xiaoni , Li, Youming and Yu, Chaohui
Publisher
England: BMJ Publishing Group LTD
Journal title
Language
English
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Publisher
England: BMJ Publishing Group LTD
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Scope and Contents
Contents
ObjectiveAccumulation of free fatty acids (FFAs) in hepatocytes induces lipotoxicity, leading to non-alcoholic fatty liver disease (NAFLD). This study aimed to investigate the underlying mechanisms by which FFA contributes to the pathogenesis of NAFLD via the regulation of 3-mercaptopyruvate sulfurtransferase (MPST), a key enzyme that regulates end...
Alternative Titles
Full title
Fatty acids promote fatty liver disease via the dysregulation of 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6241611
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6241611
Other Identifiers
ISSN
0017-5749
E-ISSN
1468-3288
DOI
10.1136/gutjnl-2017-313778