Inositol phosphates are assembly co-factors for HIV-1
Inositol phosphates are assembly co-factors for HIV-1
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Author / Creator
Dick, Robert A. , Zadrozny, Kaneil K. , Xu, Chaoyi , Schur, Florian K. M. , Lyddon, Terri D. , Ricana, Clifton L. , Wagner, Jonathan M. , Perilla, Juan R. , Ganser-Pornillos, Barbie K. , Johnson, Marc C. , Pornillos, Owen , Vogt, Volker M. and Argonne National Laboratory (ANL), Argonne, IL (United States)
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London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
A short, 14-amino-acid segment called SP1, located in the Gag structural protein
1
, has a critical role during the formation of the HIV-1 virus particle. During virus assembly, the SP1 peptide and seven preceding residues fold into a six-helix bundle, which holds together the Gag hexamer and facilitates the formation of a curved immature hex...
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Full title
Inositol phosphates are assembly co-factors for HIV-1
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6242333
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6242333
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-018-0396-4
