Pathogenicity of Ebola and Marburg Viruses Is Associated With Differential Activation of the Myeloid...
Pathogenicity of Ebola and Marburg Viruses Is Associated With Differential Activation of the Myeloid Compartment in Humanized Triple Knockout-Bone Marrow, Liver, and Thymus Mice
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United States: Oxford University Press
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Language
English
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Publisher
United States: Oxford University Press
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Ebola virus (EBOV) and Marburg virus (MARV) outbreaks are highly lethal, and infection results in a hemorrhagic fever with complex etiology. These zoonotic viruses dysregulate the immune system to cause disease, in part by replicating within myeloid cells that would normally innately control viral infection and shape the adaptive immune response. W...
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Full title
Pathogenicity of Ebola and Marburg Viruses Is Associated With Differential Activation of the Myeloid Compartment in Humanized Triple Knockout-Bone Marrow, Liver, and Thymus Mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6249575
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6249575
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ISSN
0022-1899
E-ISSN
1537-6613
DOI
10.1093/infdis/jiy269
