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Pathogenicity of Ebola and Marburg Viruses Is Associated With Differential Activation of the Myeloid...

Pathogenicity of Ebola and Marburg Viruses Is Associated With Differential Activation of the Myeloid...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6249575

Pathogenicity of Ebola and Marburg Viruses Is Associated With Differential Activation of the Myeloid Compartment in Humanized Triple Knockout-Bone Marrow, Liver, and Thymus Mice

About this item

Full title

Pathogenicity of Ebola and Marburg Viruses Is Associated With Differential Activation of the Myeloid Compartment in Humanized Triple Knockout-Bone Marrow, Liver, and Thymus Mice

Publisher

United States: Oxford University Press

Journal title

The Journal of infectious diseases, 2018-11, Vol.218 (suppl_5), p.S409-S417

Language

English

Formats

Publication information

Publisher

United States: Oxford University Press

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Ebola virus (EBOV) and Marburg virus (MARV) outbreaks are highly lethal, and infection results in a hemorrhagic fever with complex etiology. These zoonotic viruses dysregulate the immune system to cause disease, in part by replicating within myeloid cells that would normally innately control viral infection and shape the adaptive immune response. W...

Alternative Titles

Full title

Pathogenicity of Ebola and Marburg Viruses Is Associated With Differential Activation of the Myeloid Compartment in Humanized Triple Knockout-Bone Marrow, Liver, and Thymus Mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6249575

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6249575

Other Identifiers

ISSN

0022-1899

E-ISSN

1537-6613

DOI

10.1093/infdis/jiy269

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