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Sphingosine kinase 1 promotes the metastasis of colorectal cancer by inducing the epithelial‑mesench...

Sphingosine kinase 1 promotes the metastasis of colorectal cancer by inducing the epithelial‑mesench...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6254930

Sphingosine kinase 1 promotes the metastasis of colorectal cancer by inducing the epithelial‑mesenchymal transition mediated by the FAK/AKT/MMPs axis

About this item

Full title

Sphingosine kinase 1 promotes the metastasis of colorectal cancer by inducing the epithelial‑mesenchymal transition mediated by the FAK/AKT/MMPs axis

Publisher

Athens: Spandidos Publications

Journal title

International journal of oncology, 2019-01, Vol.54 (1), p.41-52

Language

English

Formats

Publication information

Publisher

Athens: Spandidos Publications

More information

Scope and Contents

Contents

It was demonstrated that Sphingosine kinase 1 (SphK1) promotes tumor progression and confers the malignancy phenotype of colorectal cancer by activating the focal adhesion kinase (FAK) pathway. However, further clarification is required to determine if SphK1 promotes the metastasis of colorectal cancer by inducing epithelial-mesenchymal transition...

Alternative Titles

Full title

Sphingosine kinase 1 promotes the metastasis of colorectal cancer by inducing the epithelial‑mesenchymal transition mediated by the FAK/AKT/MMPs axis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6254930

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6254930

Other Identifiers

ISSN

1019-6439

E-ISSN

1791-2423

DOI

10.3892/ijo.2018.4607

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