The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells
The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells
About this item
Full title
Author / Creator
Paolino, Magdalena , Choidas, Axel , Wallner, Stephanie , Pranjic, Blanka , Uribesalgo, Iris , Loeser, Stefanie , Jamieson, Amanda M. , Langdon, Wallace Y. , Ikeda, Fumiyo , Fededa, Juan Pablo , Cronin, Shane J. , Nitsch, Roberto , Schultz-Fademrecht, Carsten , Eickhoff, Jan , Menninger, Sascha , Unger, Anke , Torka, Robert , Gruber, Thomas , Hinterleitner, Reinhard , Baier, Gottfried , Wolf, Dominik , Ullrich, Axel , Klebl, Bert M. and Penninger, Josef M.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The E3 ligase Cbl-b acts on TAM tyrosine kinase receptors and has a critical role in the regulation of natural killer (NK) cell rejection of metastatic tumours; a small molecule TAM kinase inhibitor is shown to enhance the anti-metastatic NK cell activity.
Controlling NK cell anti-metastatic activity
This study describes a previously unknown...
Alternative Titles
Full title
The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells
Authors, Artists and Contributors
Author / Creator
Choidas, Axel
Wallner, Stephanie
Pranjic, Blanka
Uribesalgo, Iris
Loeser, Stefanie
Jamieson, Amanda M.
Langdon, Wallace Y.
Ikeda, Fumiyo
Fededa, Juan Pablo
Cronin, Shane J.
Nitsch, Roberto
Schultz-Fademrecht, Carsten
Eickhoff, Jan
Menninger, Sascha
Unger, Anke
Torka, Robert
Gruber, Thomas
Hinterleitner, Reinhard
Baier, Gottfried
Wolf, Dominik
Ullrich, Axel
Klebl, Bert M.
Penninger, Josef M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6258903
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6258903
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature12998
