Deregulation of CRAD-controlled cytoskeleton initiates mucinous colorectal cancer via β-catenin
Deregulation of CRAD-controlled cytoskeleton initiates mucinous colorectal cancer via β-catenin
About this item
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Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Epithelial integrity is maintained by the cytoskeleton and through cell adhesion. However, it is not yet known how a deregulated cytoskeleton is associated with cancer. We identified cancer-related regulator of actin dynamics (
CRAD
) as frequently mutated or transcriptionally downregulated in colorectal cancer. We found that CRAD stabilizes...
Alternative Titles
Full title
Deregulation of CRAD-controlled cytoskeleton initiates mucinous colorectal cancer via β-catenin
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6261439
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6261439
Other Identifiers
ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/s41556-018-0215-z
