Structures of the human pre-catalytic spliceosome and its precursor spliceosome
Structures of the human pre-catalytic spliceosome and its precursor spliceosome
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The pre-catalytic spliceosome (B complex) is preceded by its precursor spliceosome (pre-B complex) and followed by the activated spliceosome (B
act
complex). The pre-B-to-B and B-to-B
act
transitions are driven by the ATPase/helicases Prp28 and Brr2, respectively. In this study, we report the cryo-electron microscopy structures of the h...
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Full title
Structures of the human pre-catalytic spliceosome and its precursor spliceosome
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6274647
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6274647
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ISSN
1001-0602
E-ISSN
1748-7838
DOI
10.1038/s41422-018-0094-7
