Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration
Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Cancer immunotherapy has emerged as an effective therapy in a variety of cancers. However, a key challenge in the field is that only a subset of patients who receive immunotherapy exhibit durable response. It has been hypothesized that host genetics influences the inherent immune profiles of patients and may underlie their differential response to...
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Full title
Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6294879
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6294879
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ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.1804506115