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The ins and outs of MHC class II-mediated antigen processing and presentation

The ins and outs of MHC class II-mediated antigen processing and presentation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6314495

The ins and outs of MHC class II-mediated antigen processing and presentation

About this item

Full title

The ins and outs of MHC class II-mediated antigen processing and presentation

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Immunology, 2015-04, Vol.15 (4), p.203-216

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Key Points
MHC class II molecules bind antigenic peptides that are generated in endosomal–lysosomal antigen-processing compartments. These peptides are derived from proteins that access these compartments using various endocytic pathways and also as a result of autophagy.
Proteolysis in antigen-processing compartments is regulated in antigen-...

Alternative Titles

Full title

The ins and outs of MHC class II-mediated antigen processing and presentation

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6314495

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6314495

Other Identifiers

ISSN

1474-1733

E-ISSN

1474-1741

DOI

10.1038/nri3818

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