The ins and outs of MHC class II-mediated antigen processing and presentation
The ins and outs of MHC class II-mediated antigen processing and presentation
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Key Points
MHC class II molecules bind antigenic peptides that are generated in endosomal–lysosomal antigen-processing compartments. These peptides are derived from proteins that access these compartments using various endocytic pathways and also as a result of autophagy.
Proteolysis in antigen-processing compartments is regulated in antigen-...
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Full title
The ins and outs of MHC class II-mediated antigen processing and presentation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6314495
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6314495
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ISSN
1474-1733
E-ISSN
1474-1741
DOI
10.1038/nri3818