Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic ret...
Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum
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United States: The American Association for the Advancement of Science
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Language
English
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United States: The American Association for the Advancement of Science
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Contents
Many secretory and membrane proteins are modified through the attachment of sugar chains by N-glycosylation. Such modification is required for correct protein folding, targeting, and functionality. In mammalian cells, N-glycosylation is catalyzed by the oligosaccharyltransferase (OST) complex via its STT3 subunit. OST forms a complex with the ribos...
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Full title
Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6319373
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6319373
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aar7899