Efficient and precise editing of endogenous transcripts with SNAP-tagged ADARs
Efficient and precise editing of endogenous transcripts with SNAP-tagged ADARs
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Molecular tools that target RNA at specific sites allow recoding of RNA information and processing. SNAP-tagged deaminases guided by a chemically stabilized guide RNA can edit targeted adenosine to inosine in several endogenous transcripts simultaneously, with high efficiency (up to 90%), high potency, sufficient editing duration, and high precisio...
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Full title
Efficient and precise editing of endogenous transcripts with SNAP-tagged ADARs
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6322650
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6322650
Other Identifiers
ISSN
1548-7091
E-ISSN
1548-7105
DOI
10.1038/s41592-018-0017-z
