Real-time imaging of DNA loop extrusion by condensin
Real-time imaging of DNA loop extrusion by condensin
About this item
Full title
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Publisher
United States: The American Association for the Advancement of Science
Journal title
Language
English
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Publication information
Publisher
United States: The American Association for the Advancement of Science
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More information
Scope and Contents
Contents
It has been hypothesized that SMC protein complexes such as condensin and cohesin spatially organize chromosomes by extruding DNA into large loops. We directly visualized the formation and processive extension of DNA loops by yeast condensin in real time. Our findings constitute unambiguous evidence for loop extrusion. We observed that a single con...
Alternative Titles
Full title
Real-time imaging of DNA loop extrusion by condensin
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6329450
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6329450
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aar7831
