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Insufficient glutamine synthetase activity during synaptogenesis causes spatial memory impairment in...

Insufficient glutamine synthetase activity during synaptogenesis causes spatial memory impairment in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6342969

Insufficient glutamine synthetase activity during synaptogenesis causes spatial memory impairment in adult mice

About this item

Full title

Insufficient glutamine synthetase activity during synaptogenesis causes spatial memory impairment in adult mice

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2019-01, Vol.9 (1), p.252-252, Article 252

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Glutamatergic synapses constitute a major excitatory neurotransmission system and are regulated by glutamate/glutamine (Gln) cycling between neurons and astrocytes. Gln synthetase (GS) produced by astrocytes plays an important role in maintaining the cycle. However, the significance of GS during synaptogenesis has not been clarified. GS activity an...

Alternative Titles

Full title

Insufficient glutamine synthetase activity during synaptogenesis causes spatial memory impairment in adult mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6342969

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6342969

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-018-36619-2

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