Streamlining the chemoenzymatic synthesis of complex N-glycans by a stop and go strategy
Streamlining the chemoenzymatic synthesis of complex N-glycans by a stop and go strategy
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Contemporary chemoenzymatic approaches can provide highly complex multi-antennary
N
-linked glycans. These procedures are, however, very demanding and typically involve as many as 100 chemical steps to prepare advanced intermediates that can be diversified by glycosyltransferases in a branch-selective manner to give asymmetrical structures co...
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Full title
Streamlining the chemoenzymatic synthesis of complex N-glycans by a stop and go strategy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6347513
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6347513
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ISSN
1755-4330
E-ISSN
1755-4349
DOI
10.1038/s41557-018-0188-3