STING-mediated inflammation in Kupffer cells contributes to progression of nonalcoholic steatohepati...
STING-mediated inflammation in Kupffer cells contributes to progression of nonalcoholic steatohepatitis
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Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publisher
United States: American Society for Clinical Investigation
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Contents
Innate immune activation contributes to the transition from nonalcoholic fatty liver to nonalcoholic steatohepatitis (NASH). Stimulator of IFN genes (STING, also referred to Tmem173) is a universal receptor that recognizes released DNA and triggers innate immune activation. In this work, we investigated the role of STING in the progression of NASH...
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Full title
STING-mediated inflammation in Kupffer cells contributes to progression of nonalcoholic steatohepatitis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6355218
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6355218
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI121842
