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Neutrophil-induced genomic instability impedes resolution of inflammation and wound healing

Neutrophil-induced genomic instability impedes resolution of inflammation and wound healing

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6355304

Neutrophil-induced genomic instability impedes resolution of inflammation and wound healing

About this item

Full title

Neutrophil-induced genomic instability impedes resolution of inflammation and wound healing

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2019-02, Vol.129 (2), p.712-726

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Neutrophil (PMN) infiltration of the intestinal mucosa is a hallmark of tissue injury associated with inflammatory bowel diseases (IBDs). The pathological effects of PMNs are largely attributed to the release of soluble mediators and reactive oxygen species (ROS). We identified what we believe is a new, ROS-independent mechanism whereby activated t...

Alternative Titles

Full title

Neutrophil-induced genomic instability impedes resolution of inflammation and wound healing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6355304

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6355304

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI122085

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