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Targeting FLT3 mutations in AML: review of current knowledge and evidence

Targeting FLT3 mutations in AML: review of current knowledge and evidence

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6365380

Targeting FLT3 mutations in AML: review of current knowledge and evidence

About this item

Full title

Targeting FLT3 mutations in AML: review of current knowledge and evidence

Publisher

London: Nature Publishing Group UK

Journal title

Leukemia, 2019-02, Vol.33 (2), p.299-312

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Genomic investigations of acute myeloid leukemia (AML) have demonstrated that several genes are recurrently mutated, leading to new genomic classifications, predictive biomarkers, and new therapeutic targets. Mutations of the FMS-like tyrosine kinase 3 (
FLT3
) gene occur in approximately 30% of all AML cases, with the internal tandem duplica...

Alternative Titles

Full title

Targeting FLT3 mutations in AML: review of current knowledge and evidence

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6365380

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6365380

Other Identifiers

ISSN

0887-6924

E-ISSN

1476-5551

DOI

10.1038/s41375-018-0357-9

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