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Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment v...

Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment v...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6389357

Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound

About this item

Full title

Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2018-09, Vol.24 (9), p.1430-1440

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Prophylactic vaccination of rhesus macaques with rhesus cytomegalovirus (RhCMV) vectors expressing simian immunodeficiency virus (SIV) antigens (RhCMV/SIV) elicits immune responses that stringently control highly pathogenic SIV infection, with subsequent apparent clearance of the infection, in ~50% of vaccinees. In contrast, here, we show that ther...

Alternative Titles

Full title

Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6389357

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6389357

Other Identifiers

ISSN

1078-8956,1546-170X

E-ISSN

1546-170X

DOI

10.1038/s41591-018-0130-7

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