Long noncoding RNA NEXN-AS1 mitigates atherosclerosis by regulating the actin-binding protein NEXN
Long noncoding RNA NEXN-AS1 mitigates atherosclerosis by regulating the actin-binding protein NEXN
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Author / Creator
Hu, Yan-Wei , Guo, Feng-Xia , Xu, Yuan-Jun , Li, Pan , Lu, Zhi-Feng , McVey, David G , Zheng, Lei , Wang, Qian , Ye, John H , Kang, Chun-Min , Wu, Shao-Guo , Zhao, Jing-Jing , Ma, Xin , Yang, Zhen , Fang, Fu-Chun , Qiu, Yu-Rong , Xu, Bang-Ming , Xiao, Lei , Wu, Qian , Wu, Li-Mei , Ding, Li , Webb, Tom R , Samani, Nilesh J and Ye, Shu
Publisher
United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
Noncoding RNAs are emerging as important players in gene regulation and disease pathogeneses. Here, we show that a previously uncharacterized long noncoding RNA, nexilin F-actin binding protein antisense RNA 1 (NEXN-AS1), modulates the expression of the actin-binding protein NEXN and that NEXN exerts a protective role against atherosclerosis. An ex...
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Full title
Long noncoding RNA NEXN-AS1 mitigates atherosclerosis by regulating the actin-binding protein NEXN
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6391138
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6391138
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI98230
