Activation of the PERK-ATF4 pathway promotes chemo-resistance in colon cancer cells
Activation of the PERK-ATF4 pathway promotes chemo-resistance in colon cancer cells
About this item
Full title
Author / Creator
Shi, Zhong , Yu, Xiaofu , Yuan, Meiqin , Lv, Wangxia , Feng, Tingting , Bai, Rui and Zhong, Haijun
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Colon cancer is a major health problem worldwide. While chemotherapy remains a main approach for treating late-stage colon cancer patients, most, if not all, of them will develop drug resistance and die of uncontrollable disease progression eventually. Therefore, identification of mechanism of drug resistance and development of overcoming strategy...
Alternative Titles
Full title
Activation of the PERK-ATF4 pathway promotes chemo-resistance in colon cancer cells
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Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6397152
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6397152
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-39547-x