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The ERK and JNK pathways in the regulation of metabolic reprogramming

The ERK and JNK pathways in the regulation of metabolic reprogramming

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6398583

The ERK and JNK pathways in the regulation of metabolic reprogramming

About this item

Full title

The ERK and JNK pathways in the regulation of metabolic reprogramming

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2019-03, Vol.38 (13), p.2223-2240

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Most tumor cells reprogram their glucose metabolism as a result of mutations in oncogenes and tumor suppressors, leading to the constitutive activation of signaling pathways involved in cell growth. This metabolic reprogramming, known as aerobic glycolysis or the Warburg effect, allows tumor cells to sustain their fast proliferation and evade apopt...

Alternative Titles

Full title

The ERK and JNK pathways in the regulation of metabolic reprogramming

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6398583

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6398583

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/s41388-018-0582-8

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