Collagen type II suppresses articular chondrocyte hypertrophy and osteoarthritis progression by prom...
Collagen type II suppresses articular chondrocyte hypertrophy and osteoarthritis progression by promoting integrin β1-SMAD1 interaction
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Author / Creator
Lian, Chengjie , Wang, Xudong , Qiu, Xianjian , Wu, Zizhao , Gao, Bo , Liu, Lei , Liang, Guoyan , Zhou, Hang , Yang, Xiaoming , Peng, Yan , Liang, Anjing , Xu, Caixia , Huang, Dongsheng and Su, Peiqiang
Publisher
China: Springer Nature B.V
Journal title
Language
English
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Publisher
China: Springer Nature B.V
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Scope and Contents
Contents
Hypertrophic differentiation is not only the terminal process of endochondral ossification in the growth plate but is also an important pathological change in osteoarthritic cartilage. Collagen type II (COL2A1) was previously considered to be only a structural component of the cartilage matrix, but recently, it has been revealed to be an extracellu...
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Full title
Collagen type II suppresses articular chondrocyte hypertrophy and osteoarthritis progression by promoting integrin β1-SMAD1 interaction
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6403405
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6403405
Other Identifiers
ISSN
2095-4700
E-ISSN
2095-6231
DOI
10.1038/s41413-019-0046-y
