Reactive oxygen species modulate macrophage immunosuppressive phenotype through the up-regulation of...
Reactive oxygen species modulate macrophage immunosuppressive phenotype through the up-regulation of PD-L1
About this item
Full title
Author / Creator
Roux, Cecilia , Jafari, Soode Moghadas , Shinde, Rahul , Duncan, Gordon , Cescon, David W. , Silvester, Jennifer , Chu, Mandy F. , Hodgson, Kelsey , Berger, Thorsten , Wakeham, Andrew , Palomero, Luis , Garcia-Valero, Mar , Pujana, Miguel A. , Mak, Tak W. , McGaha, Tracy L. , Cappello, Paola and Gorrini, Chiara
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
The combination of immune checkpoint blockade with chemotherapy is currently under investigation as a promising strategy for the treatment of triple negative breast cancer (TNBC). Tumor-associated macrophages (TAMs) are the most prominent component of the breast cancer microenvironment because they influence tumor progression and the response to th...
Alternative Titles
Full title
Reactive oxygen species modulate macrophage immunosuppressive phenotype through the up-regulation of PD-L1
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6410837
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6410837
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1819473116
