A chemical–genetic screen identifies ABHD12 as an oxidized-phosphatidylserine lipase
A chemical–genetic screen identifies ABHD12 as an oxidized-phosphatidylserine lipase
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Publisher
New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
Reactive oxygen species (ROS) are transient, highly reactive intermediates or byproducts produced during oxygen metabolism. However, when innate mechanisms are unable to cope with sequestration of surplus ROS, oxidative stress results, in which excess ROS damage biomolecules. Oxidized phosphatidylserine (PS), a proapoptotic ‘eat me’ signal, is prod...
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Full title
A chemical–genetic screen identifies ABHD12 as an oxidized-phosphatidylserine lipase
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6420073
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6420073
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ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/s41589-018-0195-0
