Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity
Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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A defining feature of adaptive immunity is the development of long-lived memory T cells to curtail infection. Recent studies have identified a unique stem-like T-cell subset amongst exhausted CD8-positive T cells in chronic infection
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, but it remains unclear whether CD4-positive T-cell subsets with similar features exist in chroni...
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Full title
Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6420879
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6420879
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-018-0806-7