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Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity

Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6420879

Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity

About this item

Full title

Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2019-01, Vol.565 (7737), p.101-105

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

A defining feature of adaptive immunity is the development of long-lived memory T cells to curtail infection. Recent studies have identified a unique stem-like T-cell subset amongst exhausted CD8-positive T cells in chronic infection
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, but it remains unclear whether CD4-positive T-cell subsets with similar features exist in chroni...

Alternative Titles

Full title

Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6420879

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6420879

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-018-0806-7

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