Retinal transcriptome and eQTL analyses identify genes associated with age-related macular degenerat...
Retinal transcriptome and eQTL analyses identify genes associated with age-related macular degeneration
About this item
Full title
Author / Creator
Ratnapriya, Rinki , Sosina, Olukayode A. , Starostik, Margaret R. , Kwicklis, Madeline , Kapphahn, Rebecca J. , Fritsche, Lars G. , Walton, Ashley , Arvanitis, Marios , Gieser, Linn , Pietraszkiewicz, Alexandra , Montezuma, Sandra R. , Chew, Emily Y. , Battle, Alexis , Abecasis, Gonçalo R. , Ferrington, Deborah A. , Chatterjee, Nilanjan and Swaroop, Anand
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Genome-wide association studies (GWAS) have identified genetic variants at 34 loci contributing to age-related macular degeneration (AMD)
1
–
3
. We generated transcriptional profiles of postmortem retinas from 453 controls and cases at distinct stages of AMD and integrated retinal transcriptomes, covering 13,662 protein-coding and 1,46...
Alternative Titles
Full title
Retinal transcriptome and eQTL analyses identify genes associated with age-related macular degeneration
Authors, Artists and Contributors
Author / Creator
Sosina, Olukayode A.
Starostik, Margaret R.
Kwicklis, Madeline
Kapphahn, Rebecca J.
Fritsche, Lars G.
Walton, Ashley
Arvanitis, Marios
Gieser, Linn
Pietraszkiewicz, Alexandra
Montezuma, Sandra R.
Chew, Emily Y.
Battle, Alexis
Abecasis, Gonçalo R.
Ferrington, Deborah A.
Chatterjee, Nilanjan
Swaroop, Anand
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6441365
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6441365
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/s41588-019-0351-9
