SERPINB1-mediated checkpoint of inflammatory caspase activation
SERPINB1-mediated checkpoint of inflammatory caspase activation
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Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Inflammatory caspases (caspase-1, caspase-4, caspase-5 and caspase-11 (caspase-1/-4/-5/-11)) mediate host defense against microbial infections, processing pro-inflammatory cytokines and triggering pyroptosis. However, precise checkpoints are required to prevent their unsolicited activation. Here we report that serpin family B member 1 (SERPINB1) li...
Alternative Titles
Full title
SERPINB1-mediated checkpoint of inflammatory caspase activation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6450391
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6450391
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-018-0303-z
