Modeling Parkinson’s disease in midbrain-like organoids
Modeling Parkinson’s disease in midbrain-like organoids
About this item
Full title
Author / Creator
Smits, Lisa M. , Reinhardt, Lydia , Reinhardt, Peter , Glatza, Michael , Monzel, Anna S. , Stanslowsky, Nancy , Rosato-Siri, Marcelo D. , Zanon, Alessandra , Antony, Paul M. , Bellmann, Jessica , Nicklas, Sarah M. , Hemmer, Kathrin , Qing, Xiaobing , Berger, Emanuel , Kalmbach, Norman , Ehrlich, Marc , Bolognin, Silvia , Hicks, Andrew A. , Wegner, Florian , Sterneckert, Jared L. and Schwamborn, Jens C.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Modeling Parkinson’s disease (PD) using advanced experimental in vitro models is a powerful tool to study disease mechanisms and to elucidate unexplored aspects of this neurodegenerative disorder. Here, we demonstrate that three-dimensional (3D) differentiation of expandable midbrain floor plate neural progenitor cells (mfNPCs) leads to organoids t...
Alternative Titles
Full title
Modeling Parkinson’s disease in midbrain-like organoids
Authors, Artists and Contributors
Author / Creator
Reinhardt, Lydia
Reinhardt, Peter
Glatza, Michael
Monzel, Anna S.
Stanslowsky, Nancy
Rosato-Siri, Marcelo D.
Zanon, Alessandra
Antony, Paul M.
Bellmann, Jessica
Nicklas, Sarah M.
Hemmer, Kathrin
Qing, Xiaobing
Berger, Emanuel
Kalmbach, Norman
Ehrlich, Marc
Bolognin, Silvia
Hicks, Andrew A.
Wegner, Florian
Sterneckert, Jared L.
Schwamborn, Jens C.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6450999
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6450999
Other Identifiers
ISSN
2373-8057
E-ISSN
2373-8057
DOI
10.1038/s41531-019-0078-4
