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Acquired Resistance to Antibody-Drug Conjugates

Acquired Resistance to Antibody-Drug Conjugates

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6468698

Acquired Resistance to Antibody-Drug Conjugates

About this item

Full title

Acquired Resistance to Antibody-Drug Conjugates

Publisher

Switzerland: MDPI AG

Journal title

Cancers, 2019-03, Vol.11 (3), p.394

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Antibody-drug conjugates (ADCs) combine the tumor selectivity of antibodies with the potency of cytotoxic small molecules thereby constituting antibody-mediated chemotherapy. As this inherently limits the adverse effects of the chemotherapeutic, such approaches are heavily pursued by pharma and biotech companies and have resulted in four FDA (Food...

Alternative Titles

Full title

Acquired Resistance to Antibody-Drug Conjugates

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6468698

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6468698

Other Identifiers

ISSN

2072-6694

E-ISSN

2072-6694

DOI

10.3390/cancers11030394

How to access this item