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Complete biosynthetic pathways of ascofuranone and ascochlorin in Acremonium egyptiacum

Complete biosynthetic pathways of ascofuranone and ascochlorin in Acremonium egyptiacum

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6486709

Complete biosynthetic pathways of ascofuranone and ascochlorin in Acremonium egyptiacum

About this item

Full title

Complete biosynthetic pathways of ascofuranone and ascochlorin in Acremonium egyptiacum

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2019-04, Vol.116 (17), p.8269-8274

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Ascofuranone (AF) and ascochlorin (AC) are meroterpenoids produced by various filamentous fungi, including Acremonium egyptiacum (synonym: Acremonium sclerotigenum), and exhibit diverse physiological activities. In particular, AF is a promising drug candidate against African trypanosomiasis and a potential anticancer lead compound. These compounds...

Alternative Titles

Full title

Complete biosynthetic pathways of ascofuranone and ascochlorin in Acremonium egyptiacum

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6486709

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6486709

Other Identifiers

ISSN

0027-8424,1091-6490

E-ISSN

1091-6490

DOI

10.1073/pnas.1819254116

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