Single-cell whole-genome sequencing reveals the functional landscape of somatic mutations in B lymph...
Single-cell whole-genome sequencing reveals the functional landscape of somatic mutations in B lymphocytes across the human lifespan
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Accumulation of mutations in somatic cells has been implicated as a cause of aging since the 1950s. However, attempts to establish a causal relationship between somatic mutations and aging have been constrained by the lack of methods to directly identify mutational events in primary human tissues. Here we provide genome-wide mutation frequencies an...
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Full title
Single-cell whole-genome sequencing reveals the functional landscape of somatic mutations in B lymphocytes across the human lifespan
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6500118
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6500118
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1902510116
