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Cellular senescence in progenitor cells contributes to diminished remyelination potential in progres...

Cellular senescence in progenitor cells contributes to diminished remyelination potential in progres...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6500153

Cellular senescence in progenitor cells contributes to diminished remyelination potential in progressive multiple sclerosis

About this item

Full title

Cellular senescence in progenitor cells contributes to diminished remyelination potential in progressive multiple sclerosis

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2019-04, Vol.116 (18), p.9030-9039

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Cellular senescence is a form of adaptive cellular physiology associated with aging. Cellular senescence causes a proinflammatory cellular phenotype that impairs tissue regeneration, has been linked to stress, and is implicated in several human neurodegenerative diseases. We had previously determined that neural progenitor cells (NPCs) derived from...

Alternative Titles

Full title

Cellular senescence in progenitor cells contributes to diminished remyelination potential in progressive multiple sclerosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6500153

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6500153

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1818348116

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