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RNAi modulation of placental sFLT1 for the treatment of preeclampsia

RNAi modulation of placental sFLT1 for the treatment of preeclampsia

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6526074

RNAi modulation of placental sFLT1 for the treatment of preeclampsia

About this item

Full title

RNAi modulation of placental sFLT1 for the treatment of preeclampsia

Publisher

New York: Nature Publishing Group US

Journal title

Nature biotechnology, 2018-12, Vol.36 (12), p.1164-1173

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Preeclampsia, a hypertension condition with no approved therapies, is treated in monkeys by gene silencing in the placenta.
Preeclampsia is a placentally induced hypertensive disorder of pregnancy that is associated with substantial morbidity and mortality to mothers and fetuses. Clinical manifestations of preterm preeclampsia result from excess...

Alternative Titles

Full title

RNAi modulation of placental sFLT1 for the treatment of preeclampsia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6526074

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6526074

Other Identifiers

ISSN

1087-0156

E-ISSN

1546-1696

DOI

10.1038/nbt.4297

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