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Rapamycin modulates tissue aging and lifespan independently of the gut microbiota in Drosophila

Rapamycin modulates tissue aging and lifespan independently of the gut microbiota in Drosophila

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6534571

Rapamycin modulates tissue aging and lifespan independently of the gut microbiota in Drosophila

About this item

Full title

Rapamycin modulates tissue aging and lifespan independently of the gut microbiota in Drosophila

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2019-05, Vol.9 (1), p.7824-7824, Article 7824

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The FDA approved drug rapamycin can prolong lifespan in diverse species and delay the onset of age-related disease in mammals. However, a number of fundamental questions remain unanswered regarding the mechanisms by which rapamycin modulates age-related pathophysiology and lifespan. Alterations in the gut microbiota can impact host physiology, meta...

Alternative Titles

Full title

Rapamycin modulates tissue aging and lifespan independently of the gut microbiota in Drosophila

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6534571

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6534571

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-019-44106-5

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