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Maternal overnutrition programs hedonic and metabolic phenotypes across generations through sperm ts...

Maternal overnutrition programs hedonic and metabolic phenotypes across generations through sperm ts...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6534971

Maternal overnutrition programs hedonic and metabolic phenotypes across generations through sperm tsRNAs

About this item

Full title

Maternal overnutrition programs hedonic and metabolic phenotypes across generations through sperm tsRNAs

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2019-05, Vol.116 (21), p.10547-10556

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

There is a growing body of evidence linking maternal overnutrition to obesity and psychopathology that can be conserved across multiple generations. Recently, we demonstrated in a maternal high-fat diet (HFD; MHFD) mouse model that MHFD induced enhanced hedonic behaviors and obesogenic phenotypes that were conserved across three generations via the...

Alternative Titles

Full title

Maternal overnutrition programs hedonic and metabolic phenotypes across generations through sperm tsRNAs

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6534971

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6534971

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1820810116

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