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Base editing: precision chemistry on the genome and transcriptome of living cells

Base editing: precision chemistry on the genome and transcriptome of living cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6535181

Base editing: precision chemistry on the genome and transcriptome of living cells

About this item

Full title

Base editing: precision chemistry on the genome and transcriptome of living cells

Author / Creator

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Genetics, 2018-12, Vol.19 (12), p.770-788

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

RNA-guided programmable nucleases from CRISPR systems generate precise breaks in DNA or RNA at specified positions. In cells, this activity can lead to changes in DNA sequence or RNA transcript abundance. Base editing is a newer genome-editing approach that uses components from CRISPR systems together with other enzymes to directly install point mu...

Alternative Titles

Full title

Base editing: precision chemistry on the genome and transcriptome of living cells

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6535181

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6535181

Other Identifiers

ISSN

1471-0056

E-ISSN

1471-0064

DOI

10.1038/s41576-018-0059-1

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