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Anephrogenic phenotype induced by SALL1 gene knockout in pigs

Anephrogenic phenotype induced by SALL1 gene knockout in pigs

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6541644

Anephrogenic phenotype induced by SALL1 gene knockout in pigs

About this item

Full title

Anephrogenic phenotype induced by SALL1 gene knockout in pigs

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2019-05, Vol.9 (1), p.8016-8016, Article 8016

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

To combat organ shortage in transplantation medicine, a novel strategy has been proposed to generate human organs from exogenous pluripotent stem cells utilizing the developmental mechanisms of pig embryos/foetuses. Genetically modified pigs missing specific organs are key elements in this strategy. In this study, we demonstrate the feasibility of...

Alternative Titles

Full title

Anephrogenic phenotype induced by SALL1 gene knockout in pigs

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6541644

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6541644

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-019-44387-w

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