Anephrogenic phenotype induced by SALL1 gene knockout in pigs
Anephrogenic phenotype induced by SALL1 gene knockout in pigs
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
To combat organ shortage in transplantation medicine, a novel strategy has been proposed to generate human organs from exogenous pluripotent stem cells utilizing the developmental mechanisms of pig embryos/foetuses. Genetically modified pigs missing specific organs are key elements in this strategy. In this study, we demonstrate the feasibility of...
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Full title
Anephrogenic phenotype induced by SALL1 gene knockout in pigs
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6541644
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6541644
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-44387-w