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ArticlesPeer ReviewedFull Text
Arctic wildfires, hybrid embryos and record-breaking heatwave
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-08, Vol.572 (7767), p.10-11
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ArticlesPeer ReviewedFull Text
Haematopoietic stem cell self-renewal in vivo and ex vivo
Author / Creator:Wilkinson, Adam C. ; Igarashi, Kyomi J. ; Nakauchi, Hiromitsu
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Genetics, 2020-09, Vol.21 (9), p.541-554
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ArticlesPeer ReviewedFull Text
Long-term ex vivo expansion of mouse hematopoietic stem cells
Author / Creator:Wilkinson, Adam C. ; Ishida, Reiko ; Nakauchi, Hiromitsu ; Yamazaki, Satoshi
Publisher:London: Nature Publishing Group UK
Journal title:Nature protocols, 2020-02, Vol.15 (2), p.628-648
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ArticlesPeer ReviewedFull Text
Cas9-AAV6 gene correction of beta-globin in autologous HSCs improves sickle cell disease erythropoiesis in mice
Author / Creator:Wilkinson, Adam C. ; Dever, Daniel P. ; Baik, Ron ; Camarena, Joab ; Hsu, Ian ; Charlesworth, Carsten T. ; Morita, Chika ; Nakauchi, Hiromitsu ; Porteus, Matthew H.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-01, Vol.12 (1), p.686-686, Article 686
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Newsletter articlesFull Text
INTERNATIONAL PATENT: WILKINSON, ADAM, C. , NAKAUCHI, HIROMITSU , YAMAZAKI, SATOSHI , LOH, KYLE, MING , NISHIMURA, TOSHINOBU , THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY , THE UNIV...
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2021
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ArticlesPeer ReviewedFull Text
Changing concepts in hematopoietic stem cells
Author / Creator:Yamamoto, Ryo ; Wilkinson, Adam C ; Nakauchi, Hiromitsu
Publisher:United States: The American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2018-11, Vol.362 (6417), p.895-896
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ArticlesPeer ReviewedFull Text
Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation
Author / Creator:Wilkinson, Adam C. ; Ishida, Reiko ; Kikuchi, Misako ; Sudo, Kazuhiro ; Morita, Maiko ; Crisostomo, Ralph Valentine ; Yamamoto, Ryo ; Loh, Kyle M. ; Nakamura, Yukio ; Watanabe, Motoo ; Nakauchi, Hiromitsu ; Yamazaki, Satoshi
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-07, Vol.571 (7763), p.117-121
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ArticlesPeer ReviewedFull Text
Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats
Author / Creator:Goto, Teppei ; Hara, Hiromasa ; Sanbo, Makoto ; Masaki, Hideki ; Sato, Hideyuki ; Yamaguchi, Tomoyuki ; Hochi, Shinichi ; Kobayashi, Toshihiro ; Nakauchi, Hiromitsu ; Hirabayashi, Masumi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-02, Vol.10 (1), p.451-451, Article 451
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ArticlesPeer ReviewedFull Text
Depleting dietary valine permits nonmyeloablative mouse hematopoietic stem cell transplantation
Author / Creator:Taya, Yuki ; Ota, Yasunori ; Wilkinson, Adam C. ; Kanazawa, Ayano ; Watarai, Hiroshi ; Kasai, Masataka ; Nakauchi, Hiromitsu ; Yamazaki, Satoshi
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2016-12, Vol.354 (6316), p.1152-1155
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ArticlesPeer ReviewedFull Text
Hoxb5 marks long-term haematopoietic stem cells and reveals a homogenous perivascular niche
Author / Creator:Chen, James Y. ; Miyanishi, Masanori ; Wang, Sean K. ; Yamazaki, Satoshi ; Sinha, Rahul ; Kao, Kevin S. ; Seita, Jun ; Sahoo, Debashis ; Nakauchi, Hiromitsu ; Weissman, Irving L.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-02, Vol.530 (7589), p.223-227
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ArticlesPeer ReviewedFull Text
Investigation of Cas9 antibodies in the human eye
Author / Creator:Toral, Marcus A. ; Charlesworth, Carsten T. ; Ng, Benjamin ; Chemudupati, Teja ; Homma, Shota ; Nakauchi, Hiromitsu ; Bassuk, Alexander G. ; Porteus, Matthew H. ; Mahajan, Vinit B.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-02, Vol.13 (1), p.1053-1053, Article 1053
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ArticlesPeer ReviewedFull Text
Chemically defined cytokine-free expansion of human haematopoietic stem cells
Author / Creator:Sakurai, Masatoshi ; Ishitsuka, Kantaro ; Ito, Ryoji ; Wilkinson, Adam C. ; Kimura, Takaharu ; Mizutani, Eiji ; Nishikii, Hidekazu ; Sudo, Kazuhiro ; Becker, Hans Jiro ; Takemoto, Hiroshi ; Sano, Tsubasa ; Kataoka, Keisuke ; Takahashi, Satoshi ; Nakamura, Yukio ; Kent, David G. ; Iwama, Atsushi ; Chiba, Shigeru ; Okamoto, Shinichiro ; Nakauchi, Hiromitsu ; Yamazaki, Satoshi
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2023-03, Vol.615 (7950), p.127-133
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ArticlesPeer ReviewedFull Text
Frequent pathway mutations of splicing machinery in myelodysplasia
Author / Creator:Yoshida, Kenichi ; Sanada, Masashi ; Shiraishi, Yuichi ; Nowak, Daniel ; Nagata, Yasunobu ; Yamamoto, Ryo ; Sato, Yusuke ; Sato-Otsubo, Aiko ; Kon, Ayana ; Nagasaki, Masao ; Chalkidis, George ; Suzuki, Yutaka ; Shiosaka, Masashi ; Kawahata, Ryoichiro ; Yamaguchi, Tomoyuki ; Otsu, Makoto ; Obara, Naoshi ; Sakata-Yanagimoto, Mamiko ; Ishiyama, Ken ; Mori, Hiraku ; Nolte, Florian ; Hofmann, Wolf-Karsten ; Miyawaki, Shuichi ; Sugano, Sumio ; Haferlach, Claudia ; Koeffler, H. Phillip ; Shih, Lee-Yung ; Haferlach, Torsten ; Chiba, Shigeru ; Nakauchi, Hiromitsu ; Miyano, Satoru ; Ogawa, Seishi
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2011-10, Vol.478 (7367), p.64-69
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ArticlesPeer ReviewedFull Text
CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep
Author / Creator:Vilarino, Marcela ; Rashid, Sheikh Tamir ; Suchy, Fabian Patrik ; McNabb, Bret Roberts ; van der Meulen, Talitha ; Fine, Eli J. ; Ahsan, Syed Daniyal ; Mursaliyev, Nurlybek ; Sebastiano, Vittorio ; Diab, Santiago Sain ; Huising, Mark O. ; Nakauchi, Hiromitsu ; Ross, Pablo J.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-12, Vol.7 (1), p.17472-17472, Article 17472
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ArticlesPeer ReviewedFull Text
Establishment of mouse expanded potential stem cells
Author / Creator:Yang, Jian ; Ryan, David J. ; Wang, Wei ; Tsang, Jason Cheuk-Ho ; Lan, Guocheng ; Masaki, Hideki ; Gao, Xuefei ; Antunes, Liliana ; Yu, Yong ; Zhu, Zhexin ; Wang, Juexuan ; Kolodziejczyk, Aleksandra A. ; Campos, Lia S. ; Wang, Cui ; Yang, Fengtang ; Zhong, Zhen ; Fu, Beiyuan ; Eckersley-Maslin, Melanie A. ; Woods, Michael ; Tanaka, Yosuke ; Chen, Xi ; Wilkinson, Adam C. ; Bussell, James ; White, Jacqui ; Ramirez-Solis, Ramiro ; Reik, Wolf ; Göttgens, Berthold ; Teichmann, Sarah A. ; Tam, Patrick P. L. ; Nakauchi, Hiromitsu ; Zou, Xiangang ; Lu, Liming ; Liu, Pentao
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-10, Vol.550 (7676), p.393-397
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ArticlesPeer ReviewedFull Text
Generation of functional lungs via conditional blastocyst complementation using pluripotent stem cells
Author / Creator:Mori, Munemasa ; Furuhashi, Kazuhiro ; Danielsson, Jennifer A. ; Hirata, Yuichi ; Kakiuchi, Miwako ; Lin, Chyuan-Sheng ; Ohta, Mayu ; Riccio, Paul ; Takahashi, Yusuke ; Xu, Xinjing ; Emala, Charles W. ; Lu, Chao ; Nakauchi, Hiromitsu ; Cardoso, Wellington V.
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2019-11, Vol.25 (11), p.1691-1698
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ArticlesPeer ReviewedFull Text
Blastocyst complementation generates exogenic pancreas in vivo in apancreatic cloned pigs
Author / Creator:Matsunari, Hitomi ; Nagashima, Hiroshi ; Watanabe, Masahito ; Umeyama, Kazuhiro ; Nakano, Kazuaki ; Nagaya, Masaki ; Kobayashi, Toshihiro ; Yamaguchi, Tomoyuki ; Sumazaki, Ryo ; Herzenberg, Leonard A. ; Nakauchi, Hiromitsu
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-03, Vol.110 (12), p.4557-4562
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ArticlesPeer ReviewedFull Text
An in vitro expansion system for generation of human iPS cell-derived hepatic progenitor-like cells exhibiting a bipotent differentiation potential
Author / Creator:Yanagida, Ayaka ; Ito, Keiichi ; Chikada, Hiromi ; Nakauchi, Hiromitsu ; Kamiya, Akihide
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-07, Vol.8 (7), p.e67541-e67541
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ArticlesPeer ReviewedFull Text
Blastocyst complementation using Prdm14-deficient rats enables efficient germline transmission and generation of functional mouse spermatids in rats
Author / Creator:Kobayashi, Toshihiro ; Goto, Teppei ; Oikawa, Mami ; Sanbo, Makoto ; Yoshida, Fumika ; Terada, Reiko ; Niizeki, Naoko ; Kajitani, Naoyo ; Kazuki, Kanako ; Kazuki, Yasuhiro ; Hochi, Shinichi ; Nakauchi, Hiromitsu ; Surani, M. Azim ; Hirabayashi, Masumi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-02, Vol.12 (1), p.1328-1328, Article 1328
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ArticlesPeer ReviewedFull Text
Generation of heterozygous PKD1 mutant pigs exhibiting early-onset renal cyst formation
Author / Creator:Watanabe, Masahito ; Umeyama, Kazuhiro ; Nakano, Kazuaki ; Matsunari, Hitomi ; Fukuda, Toru ; Matsumoto, Kei ; Tajiri, Susumu ; Yamanaka, Shuichiro ; Hasegawa, Koki ; Okamoto, Kazutoshi ; Uchikura, Ayuko ; Takayanagi, Shuko ; Nagaya, Masaki ; Yokoo, Takashi ; Nakauchi, Hiromitsu ; Nagashima, Hiroshi
Publisher:New York: Elsevier Inc
Journal title:Laboratory investigation, 2022-05, Vol.102 (5), p.560-569
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Arctic wildfires, hybrid embryos and record-breaking heatwave

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Haematopoietic stem cell self-renewal in vivo and ex vivo

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Long-term ex vivo expansion of mouse hematopoietic stem cells

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Cas9-AAV6 gene correction of beta-globin in autologous HSCs improves sickle cell disease erythropoiesis in mice

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INTERNATIONAL PATENT: WILKINSON, ADAM, C. , NAKAUCHI, HIROMITSU , YAMAZAKI, SATOSHI , LOH, KYLE, MING , NISHIMURA, TOSHINOBU , THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY , THE UNIV...

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Changing concepts in hematopoietic stem cells

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Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation

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Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats

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Depleting dietary valine permits nonmyeloablative mouse hematopoietic stem cell transplantation

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Hoxb5 marks long-term haematopoietic stem cells and reveals a homogenous perivascular niche

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Investigation of Cas9 antibodies in the human eye

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Chemically defined cytokine-free expansion of human haematopoietic stem cells

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Frequent pathway mutations of splicing machinery in myelodysplasia

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CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep

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Establishment of mouse expanded potential stem cells

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Generation of functional lungs via conditional blastocyst complementation using pluripotent stem cells

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Blastocyst complementation generates exogenic pancreas in vivo in apancreatic cloned pigs

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An in vitro expansion system for generation of human iPS cell-derived hepatic progenitor-like cells exhibiting a bipotent differentiation potential

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Blastocyst complementation using Prdm14-deficient rats enables efficient germline transmission and generation of functional mouse spermatids in rats

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Generation of heterozygous PKD1 mutant pigs exhibiting early-onset renal cyst formation

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