Therapeutic benefit of combining calorie-restricted ketogenic diet and glutamine targeting in late-s...
Therapeutic benefit of combining calorie-restricted ketogenic diet and glutamine targeting in late-stage experimental glioblastoma
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Glioblastoma (GBM) is an aggressive primary human brain tumour that has resisted effective therapy for decades. Although glucose and glutamine are the major fuels that drive GBM growth and invasion, few studies have targeted these fuels for therapeutic management. The glutamine antagonist, 6-diazo-5-oxo-L-norleucine (DON), was administered together...
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Therapeutic benefit of combining calorie-restricted ketogenic diet and glutamine targeting in late-stage experimental glioblastoma
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6541653
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6541653
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ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-019-0455-x
