Runx2 stimulates neoangiogenesis through the Runt domain in melanoma
Runx2 stimulates neoangiogenesis through the Runt domain in melanoma
About this item
Full title
Author / Creator
Cecconi, Daniela , Brandi, Jessica , Manfredi, Marcello , Serena, Michela , Dalle Carbonare, Luca , Deiana, Michela , Cheri, Samuele , Parolini, Francesca , Gandini, Alberto , Marchetto, Giulia , Innamorati, Giulio , Avanzi, Francesco , Antoniazzi, Franco , Marengo, Emilio , Tiso, Natascia , Mottes, Monica , Zipeto, Donato and Valenti, Maria Teresa
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Runx2 is a transcription factor involved in melanoma cell migration and proliferation. Here, we extended the analysis of Runt domain of Runx2 in melanoma cells to deepen understanding of the underlying mechanisms. By the CRISPR/Cas9 system we generated the Runt KO melanoma cells 3G8. Interestingly, the proteome analysis showed a specific protein si...
Alternative Titles
Full title
Runx2 stimulates neoangiogenesis through the Runt domain in melanoma
Authors, Artists and Contributors
Author / Creator
Brandi, Jessica
Manfredi, Marcello
Serena, Michela
Dalle Carbonare, Luca
Deiana, Michela
Cheri, Samuele
Parolini, Francesca
Gandini, Alberto
Marchetto, Giulia
Innamorati, Giulio
Avanzi, Francesco
Antoniazzi, Franco
Marengo, Emilio
Tiso, Natascia
Mottes, Monica
Zipeto, Donato
Valenti, Maria Teresa
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6541657
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6541657
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-44552-1
